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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '472f70bd6d046f4134d00d33bcefe739243f1afe05feff2c65261d6b16b5b4fb' 
  AND token = 'h4BxEGyNN/JD7Xs3VpT+53LSjBpmYYrZT3NLYZTxLxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}