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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d18e4a32f8200f576db405cf63d54fc1570f420819b049fb263066daa11d78' 
  AND token = 'Mb/0sa6jutPixOcoLSpaQR/ZmsUbCPvHrkAGZOrx4o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}