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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50d398235d36a8b1b5ca8812eb7366ac41edda8cb0eb27a658a833ac090c54e3' 
  AND token = '8JAiBlmcvARhsCekbI3780+r3Uioh/kXlWCgNfovZeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}