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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b499d3840d4c9d039634512b1e2c6d411a43315c69c3b7f92d0d850dd83523a' 
  AND token = '5Reavkl2p/XowEIF+zJHfI8gBcc+8GOgUM23ymA6GS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}