SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4a922c145ab97ec251b104be4b5c41dde94676515752fe0ae9ad5ebe7784f45' 
  AND token = 'H0uGaXtJvNu7qTTDL7TbMXeyB9aKG0UfQe4Y49opQJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}