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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa5e7c4e792a3947a6ff3278df704e73705b8def272eaed195168aa113a50534' 
  AND token = 'HB674Whx5VRwBFARhD1XjzYFlHysdGT9zD9y1pEhW0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}