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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3780a6ea8fbe781883750f5c7feb35c78292b76701aff88f3287b866de92a833' 
  AND token = 'hc1gwC0kr3tbN/9UaJzzUMIDQfDDt+U8ROJ2Tp7Rgzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}