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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e983cf53e9fc85c15eff9323f63e47695174624cfedfbf67489e188db175c5' 
  AND token = 'OBXJFxh4ls/5sSiaPdM7I4QCSJGIFWiOwI4z2sTPpTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00079

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}