SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5063aa33e8926bcb7921bf52616d14a290678c9cf494634d4bc0d8852ccbce1c' 
  AND token = 'aNrlGWrlWCoKM3y03EVUXIyxPFcKawnx5NLIIV8fNnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}