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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9065a25f104ea97a313d5d46ba0e663eeed2a1632553048af23465457c9a522' 
  AND token = 'zirgEzeF8rKthI04Eb/CbqIp53m1PVU1Cb1uLZ1On+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}