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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'deb6ad6ddc17a42e5e544c9eee2c93922584cdaa859ed8b09d487d8e41ee6260' 
  AND token = 'M0BEv7gdW0bpnSVCWuChU3EwmJWI1myOTAh7H36BI2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}