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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '197a7f91447e7f48a6fe08556c1c43135096872f88a7bb84df9af518fc7507f4' 
  AND token = 'duh113/KUrhAwwLMT/6E0QsVb13oowAkTkdSSeABKyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}