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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b6d6d165d3cf2d3c33b1b7646639ac2a04f5de37007a9bc6b42149cf76284b7' 
  AND token = 'xWnSS4Bs5QbhL5xDYJwYpYtZ1CW7crj/oXey1fqpZLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}