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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5352fd1752618e2bf201a6d350bc54e0054444cb934b2902529aee1eb12149af' 
  AND token = 'vANVxs6+gkEg9nRzRe+QvGL5bXR0EQsVVOD60pFLy9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}