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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a26b6efca68d20f76004b1d7536b9b1c9d1eb82544006f0329a7f2203c8e78f' 
  AND token = '2bDHqEIJBTlnCzxIkXQy4fcdtCXgUWjxQ0gQDbVLOxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}