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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73685aa03422ac8d5fd5ed6f6b7600a622fcdbcf5fae385aadc0c9564ff9efee' 
  AND token = 'hwR64Lr6/VlJ2TrXPdBgSkBFbd6ZyCd3e/EMneqw8wY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}