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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99e19bac11c68ded339ceaccbb69f3a3364943bf35872a197eb4ca69c11071a4' 
  AND token = '+8NDnK2sUWpRCtBCCE8ro/VnoaJ2Tb6HBA8mk/Ethzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00079

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}