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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79b4512ef1bf09c3f44260b1a1a364f40b09e0f6a4b35e55e09a49f47b51121a' 
  AND token = 'PUTsggMb1c5ZKSGY8FbMBzrpN5cMsphxaT0s75jfWUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}