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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29e8151276d5d2f55c33187ed2d2bed5288c4718d27de073042c1e7be93f4df3' 
  AND token = 'tiUldTV+Ak3dG+jVeAfdS+DAOz/Ju+ltjlWXl+UNUX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}