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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f4621e68a03fb04cf3c57f9f72c6fa95e49c184e4c04f2e628b4c2c10ffc323' 
  AND token = '5emTmvaIGgh6hj7rAsStKmWv4xkD8zdiQgqJ5qkwQFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}