SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21fa79087ae3de664e48366a57793c0a9a176a65ba360127f5b388b447c69fac' 
  AND token = 'x8YG0BQYhOS6/6jurjw7bASVi9bSRoeDkpoorK36+CI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}