SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40b7ce5619b0ee3558bc0cd21679be2d5c3269e783725c9a0ed7e410d8e8fc53' 
  AND token = 'eGvxAk1ORrd4GzAejDEW+E2U0wu3ZMXvKxsmkE0OLOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}