SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14088bd6ae04e9020a1a71970d463dcd029c605a4859e09198deafdb603f0f1e' 
  AND token = 'dFbM6C+v7Fn/vyMI6IkL9LFqwB49y2QjaK31wiC2zIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}