SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5be7d854c29873ce54c4c150ae91c6d5418ac7b58de6ab0df81ec22fef3921b2' 
  AND token = 'I/rjkHXPRI15++yPHrfiZ1NFjOgoTfdhlvr2fjPR/18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}