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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac0b072af55634dd8e1fdb797f96ee28a1e119510928b0113af00e64aacba212' 
  AND token = '+PW46vqzNt4S8Y188Y0bfbqpmaPKYJOjEcua4O/E6Pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}