SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61c27916ee86b952f04542c3a71f1671ca946feb07520a8fd51abfbfe8662b04' 
  AND token = 'O8QZLo6us7/jimdd8zU/MTOTUGUbn+jbfQplrd1VScs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}