SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42880f08e18a8ad8df1350dc0b040ac6111f5ae9524a01baa230b990c930494a' 
  AND token = 'mAIroPC8Hyaef7u5WiHf+TDj18XUyEkl5XMkF2NoeuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}