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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b493638ce06fcfa17bfa240debfab6385cda244a4024c81133b2a7e2ba8dc710' 
  AND token = '3iu0qDS0D3Cm2fqZmMMZG3to86YrvU/pkUmfC53tYtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}