SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9778b9014897d3648140e649b86db5c6b3a5b415c158967a3f8ab266585f6d2d' 
  AND token = 'CVTqnMxZ2xb8XkrTdIEsfotp+5AA5PAZVVxnsiTjnSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}