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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d27021840fc9ef04a28a10ee1c778251a530dd2b72a7dfde2dee6536eb8faf1' 
  AND token = 's6RVxjWyjCFcBqYj/F3xidL0zO4DTcSi9XAM0Jmq68o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}