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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '741696ef6914d301d847eb550ffb96c0adf5505246a6b0f4c77d8e290d59c748' 
  AND token = 'sTREyAz+DtE5pNUoAl20V0FXTc6nY992hIfiMjfAcL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}