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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af6ce9bce143f1616650edb35a615d7c9ac3b320288a38e08b29b7369e8d0c45' 
  AND token = 'dH1bir5LAJ2XBWn+GsEuREO4poRXbdiv371EJD5jQyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}