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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b8db0e257bd3c619ba773d15d9aa4d555ab04ccf77ac2819a431976d252e2a6' 
  AND token = 'k4V7G2UGxuwlgbUFUNyNHz2Z98oBSi8NkKT8lM2+vO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}