SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a585ada110d005b520c764b86f3f3de297aa9278a9d6a44e5c72e83df78215a' 
  AND token = 'RCHph7th+RgJBIp8BUOIvFWUKJeKwNJ8r7gN5h79MMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}