SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ece6dace62259c9cc2a6d2e3355d78554de1488157ca3d449c896e07717fdf17' 
  AND token = '9C+VAPYVJiVi8kMLmz7w7LoGUQu4XYrQfDz5ujfOHOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}