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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a15fd9f2da9b27cddc720aa580e04d1114a2edab204332a4cb33ea8dd93a6925' 
  AND token = 'V1L7A9F8Qo9TWaAtZ3GyGzxCe5j2LWmVJv27q4cbE+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}