SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '921672172b8d851b9e57300248fc05aefb4759658eea2b1346fc7ca946d0d483' 
  AND token = 'GMBVPUx93kwdqV4Qhcg7aAQXTbmdcDkGoXBQGYrZEk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}