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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3649a20b2b7ae06e6e50113204b43ff2c0bb159e1ba219fc7f69ee8b386ba0dd' 
  AND token = '9BSwuQ5BY1VHwIc8yrtdUogvWnew9qJ1PQNSIQg48U0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}