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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e776a7cbef9a7f07b30c69fe371096e2955488d790e1130591d9b3a104c3a1bb' 
  AND token = 'iO67zZocLFzDRIZTq86tV4CVU5sltnckEaiKg2unbHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}