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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8a486a02bbab02dc4c5208b93885018949afb8f7b2be942e36ad9b7b25f792' 
  AND token = '2sa9L5AI/AxLfE1BD/+Ke8UvNfT6I471OudYEh4G0rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}