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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00e6cf8022c97fcb726f31f3d329db70554b1282ec2b034d6451f58b55239fbb' 
  AND token = 'FQFRth6N5i0gbvWBR0jWjn+DeeOyEXu4CPix6UdU/sI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}