SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c970ecdef688fa42d89cedee4b94abf964dc4a9e7eebea7c45b81b698db509a0' 
  AND token = 'voltXdS4cxT1730Yh052gpGwhOsDHMld3aDcjF9yOnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}