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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df6a0d458d74a4a7a66287a38a1bbda7695b6e16118f854162ea1eb626876af' 
  AND token = '8OeCVGg2c6OayqBVnLSnjfGwxHHTF7//4N2uzb4BJ/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}