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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '498e5e34a81875528d0f95bb0311ca3c314014e3bbf6006689d33dd734a35243' 
  AND token = 'yy4J6HVR7eby3dyokTk4or0Uy6PCVxvwkULqvQsOEW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}