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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db3b59cc87339458160af91712e2e4074aef217af60df4eb7bb8352c488d6149' 
  AND token = '8dVOHrON0iLrTYWh080K/KbS7UqLzey1jqMG3q+mPUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}