SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4af6aa3f6bdcb1c898fe81df68700dd074248de246412fe421540efa72f8fa26' 
  AND token = 'jeRD1NgNaDJ7DZXCc8ERvdWe3XxIT2oaeaawcf5L2pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}