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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '961fbb9e52cb549e9f4f8cd040e3d8c96923602a278ff17fffc680fa93b5c944' 
  AND token = 'hxAiKM6UZY4o1kb/dCM92C3kgZ3FP6OkmkWwvbUiQ8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}