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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f43e5f4145d8d32902bbaffa6dfb6cfe3e08b5d300c44bc5a4ce9ec40d1318f' 
  AND token = '5AOPYA1lSsJTcmEEVGg7ZzPYhGsEvfF4S67LFuSOPkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}