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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0f3deff5d683a566653a1e80973f28aef71c85380ea79327cf77c53f28081da' 
  AND token = 'ZWU6ijPWyDsB3aqSnhi7lQqo0RIFvyDwGd4YY74wdlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}