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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9edf0dc50ade91357facd8b7d2b870702fd23a496ef3c5597b0674197cef4d02' 
  AND token = 'JH4WUtdY6zvS+IeHW0conIR4MlLDWdDszb2HwcAw7dM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}